LEP Polyclonal Antibody
RD75027A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLEP
Overview
- SupplierReddot Biotech
- Product NameLEP Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID3952
- Target nameLEP
- Target descriptionleptin
- Target synonymsLEPD; leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); OB; obese protein; obese, mouse, homolog of; obesity factor; OBS
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203