Lepadin H

Biorbyt

Lepadin H

10

Research Use Only

98.00%

C26H45NO3

419.64

Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing lipid peroxidation. It simultaneously decreases SLC7A11 and GPX4 levels while upregulating ACSL4 expression, thereby inducing ferroptosis via the p53-SLC7A11-GPX4 pathway [1].

C(CCC[C@@H](CCC)O)[C@@H]1[C@]2([C@](N[C@@H](C)[C@H](OC(/C=C/C=C/CCC)=O)C2)(CCC1)[H])[H]

-20°C

12352200