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Lesogaberan (hydrochloride)

HY-10061B
MedChem Express
Estimated Purity98.0
DownloadMSDS
Product group Chemicals
Molecular Weight177.54
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lesogaberan (hydrochloride)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C3H10ClFNO2P
  • Molecular Weight
    177.54
  • Scientific Description
    Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABA B receptor agonist with an EC 50 of 8.6 nM for human recombinant GABA B receptor. The affinity ( K i s) of Lesogaberan hydrochloride for rat GABA B and GABA A receptors, as measured by displacement of [ 3 H]GABA binding in brain membranes: 5.1 nM and 1.4 microM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action [1] .
  • SMILES
    O=P(C[C@H](F)CN)O.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200