Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His)

TargetMol Chemicals

Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His)

16

Research Use Only

38.3 kDa (predicted)

Virulence factor that plays an important role in immune evasion. Lyses human lymphocytes and monocytes. Binds to the LFA-1 integrin on the surface of the host cell and to cholesterol-containing membranes, which probably results in large LtxA-LFA-1 clusters in lipid rafts. Shows also beta-hemolytic activity on certain types of growth media. Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 38.3 kDa and the accession number is P16462.

-20°C

12352200