Leukotriene B5
HY-113484
Overview
- SupplierMedChem Express
- Product NameLeukotriene B5 [80445-66-5]
- Delivery Days Customer5
- CAS Number80445-66-5
- CertificationResearch Use Only
- Molecular FormulaC20H30O4
- Molecular Weight334.45
- Scientific DescriptionLeukotriene B5 (LTB5) is a leukotriene with diverse biological activities. It is a metabolite of eicosapentaenoic acid formed through the 5-lipoxygenase (5-LO) pathway. LTB5 increases contraction of bullfrog lung strips ex vivo in a concentration-dependent manner. In vivo, LTB5 (100 nM) reduces tumor volume in mice injected with Tm1 murine melanoma cells. LTB5 also elicits chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes (PMNLs) 20- to 30-fold less, and induces platelet aggregation 8-fold less, potently than LTB4.
- SMILESCC/C=C\C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O
- UNSPSC12352200