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Leukotriene B5

Research Use Only
HY-113484
MedChem Express
CAS Number80445-66-5
Product group Chemicals
Molecular Weight334.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Leukotriene B5 [80445-66-5]
  • Delivery Days Customer
    5
  • CAS Number
    80445-66-5
  • Certification
    Research Use Only
  • Molecular Formula
    C20H30O4
  • Molecular Weight
    334.45
  • Scientific Description
    Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities. It is a metabolite of eicosapentaenoic acid formed through the 5-lipoxygenase (5-LO) pathway. LTB5 increases contraction of bullfrog lung strips ex vivo in a concentration-dependent manner. In vivo, LTB5 (100 nM) reduces tumor volume in mice injected with Tm1 murine melanoma cells. LTB5 also elicits chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes (PMNLs) 20- to 30-fold less, and induces platelet aggregation 8-fold less, potently than LTB4.
  • SMILES
    CC/C=C\C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O
  • UNSPSC
    12352200