LeuRS-IN-1 hydrochloride [1364683-67-9]

TargetMol Chemicals

LeuRS-IN-1 hydrochloride [1364683-67-9]

16

1364683-67-9

Chemical

Research Use Only

LeuRS-IN-1 hydrochloride

C10H14BCl2NO3

277.94

LeuRS-IN-1 hydrochloride is a potent and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS), with IC50 and Kd values of 0.06 microM and 0.075 microM, respectively, for M.tb LeuRS. Additionally, LeuRS-IN-1 hydrochloride inhibits human cytoplasmic LeuRS with an IC50 of 38.8 microM and HepG2 protein synthesis with an EC50 of 19.6 microM.

3 years

Cl.CCOc1ccc(Cl)c2[C@@H](CN)OB(O)c12

-20°C

51202000