WB analysis of human fetal muscle tissue using GTX46596 LFNG antibody at 0.2-1microg/ml.
WB analysis of human fetal muscle tissue using GTX46596 LFNG antibody at 0.2-1microg/ml.
LFNG antibody, N-term
GTX46596
Overview
- SupplierGeneTex
- Product NameLFNG antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID3955
- Target nameLFNG
- Target descriptionLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Target synonymsbeta-1,3-N-acetylglucosaminyltransferase lunatic fringe; SCDO3
- HostRabbit
- IsotypeIgG
- Protein IDQ8NES3
- Protein NameBeta-1,3-N-acetylglucosaminyltransferase lunatic fringe
- Scientific DescriptionThis gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the MFNG (GeneID: 4242) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. [provided by RefSeq, May 2018]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203