LGI1 Antibody: PerCP

Biorbyt

LGI1 antibody

16

1 microg/ml of SMC-461 was sufficient for detection of LGI1 in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry

WB (1:1000) ELISA, ICC, IF, IHC, WB

Research Use Only

Monoclonal

N283/7 (Formerly sold as S283-7)

1 mg/ml

PerCP

Lgi1

leucine-rich repeat LGI family, member 1

BB130740; leucine-rich glioma-inactivated protein 1

Mouse

IgG2a

Leucine-rich glioma-inactivated protein 1

Mouse monoclonal to LGI1 (PerCP). The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist; this LGI1 antibody will recognize only the longer form..

Human, Mouse, Rat

See Manual

12352203