LGMN Protein, Human, Recombinant (His)

TargetMol Chemicals

LGMN Protein, Human, Recombinant (His)

16

Research Use Only

48.6 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid beta-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimers disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD.

-20°C

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