Western Blot Positive WB detected in: SH-SY5Y whole cell lysate, Rat brain tissue All lanes: LGR5 antibody at 1:1500 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 100, 98, 93 kDa Observed band size: 100 kDa
Western Blot Positive WB detected in: SH-SY5Y whole cell lysate, Rat brain tissue All lanes: LGR5 antibody at 1:1500 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 100, 98, 93 kDa Observed band size: 100 kDa
LGR5 Recombinant Monoclonal Antibody
CSB-RA262034A0HU
ApplicationsFlow Cytometry, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetLGR5
Overview
- SupplierCusabio
- Product NameLGR5 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsFlow Cytometry, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID4H8
- ConjugateUnconjugated
- Gene ID8549
- Target nameLGR5
- Target descriptionleucine rich repeat containing G protein-coupled receptor 5
- Target synonymsFEX; GPR49; GPR67; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GRP49; HG38; leucine-rich repeat-containing G-protein coupled receptor 5; orphan G protein-coupled receptor HG38
- IsotypeIgG
- Protein IDO75473
- Protein NameLeucine-rich repeat-containing G-protein coupled receptor 5
- Scientific DescriptionReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203