LH2-051 [2358754-22-8]

TargetMol Chemicals

LH2-051 [2358754-22-8]

9

Research Use Only

C27H34N2O3

434.57

LH2-051 is a lysosomal-enhancing lead compound that stimulates lysosomal biosynthesis and the clearance of Abeta aggregates through the dopamine transporter-cell cycle protein dependent kinase 9-transcription factor EB (DAT-CDK9-TFEB) pathway. Demonstrating favorable pharmacokinetic properties in mouse models, LH2-051 has the potential to improve Alzheimers disease outcomes.

O(C=1C=C2C(=CC1OC)C(N(CC2)CC3CCOCC3)CCC4=CNC=5C=CC=CC54)C

-20°C

12352200