LILRA3 antibody [N2C2], Internal
![Research Use Only](static/images/certificates/ruo.jpg)
GTX108819
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetLILRA3
Overview
- SupplierGeneTex
- Product NameLILRA3 antibody [N2C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID11026
- Target nameLILRA3
- Target descriptionleukocyte immunoglobulin like receptor A3
- Target synonymsCD85 antigen-like family member E; CD85E; HM31; HM43; ILT6; ILT-6; immunoglobulin-like transcript 6; leucocyte Ig-like receptor A3; leukocyte immunoglobulin-like receptor 4; leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3; LIR4; LIR-4; monocyte inhibitory receptor HM43/HM31
- HostRabbit
- IsotypeIgG
- Protein IDQ8N6C8
- Protein NameLeukocyte immunoglobulin-like receptor subfamily A member 3
- Scientific DescriptionLeukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Leukocyte immunoglobulin-like receptor A3 is increased in IBD patients and functions as an anti-inflammatory modulator. Lan X et al., 2021 Feb, Clin Exp ImmunolRead more