Western Blot Positive WB detected in: THP-1 whole cell lysate, Rat brain tissue All lanes: LILRB1 antibody at 3.5microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 71, 72, 50 kDa Observed band size: 71 kDa
LILRB1 Antibody
CSB-PA847747LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetLILRB1
Overview
- SupplierCusabio
- Product NameLILRB1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10859
- Target nameLILRB1
- Target descriptionleukocyte immunoglobulin like receptor B1
- Target synonymsCD85 antigen-like family member J; CD85J; Ig-like transcript 2; ILT2; ILT-2; immunoglobulin heavy chain variable region; leucocyte Ig-like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LIR1; LIR-1; MIR7; MIR-7; monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B
- HostRabbit
- IsotypeIgG
- Protein IDQ8NHL6
- Protein NameLeukocyte immunoglobulin-like receptor subfamily B member 1
- Scientific DescriptionReceptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203