LILRB1 Polyclonal Antibody
RD75237A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetLILRB1
Overview
- SupplierReddot Biotech
- Product NameLILRB1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID10859
- Target nameLILRB1
- Target descriptionleukocyte immunoglobulin like receptor B1
- Target synonymsCD85 antigen-like family member J; CD85J; Ig-like transcript 2; ILT2; ILT-2; immunoglobulin heavy chain variable region; leucocyte Ig-like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LIR1; LIR-1; MIR7; MIR-7; monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203