limertinib

MedChem Express

limertinib [1934259-00-3]

10

1934259-00-3

Research Use Only

99.12

C29H32ClN7O2

546.06

limertinib (ASK120067) is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). limertinib is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1].

O=C(NC1=CC(NC2=NC=C(C(NC3=CC4=C(C=CC=C4)C=C3)=N2)Cl)=C(C=C1N(CCN(C)C)C)OC)C=C

-20°C,2°C to 8°C

12352200