Western Blot analysis of Mouse liver tissue and k562 cell, hela and 293T cell using LIN28B Polyclonal Antibody at dilution of 1:550
LIN28B Polyclonal Antibody
E-AB-13008
Product group Antibodies
Overview
- SupplierElabscience
- Product NameLIN28B Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionThe protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3 UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
- UNSPSC12352203