LIN28B Polyclonal Antibody
RD78858A
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetLIN28B
Overview
- SupplierReddot Biotech
- Product NameLIN28B Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID389421
- Target nameLIN28B
- Target descriptionlin-28 homolog B
- Target synonymsCSDD2; Lin-28.2; lin-28B; protein lin-28 homolog B
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3 UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203