Linagliptin (GSK2118436)

Selleck Chemicals

Linagliptin (BI-1356) [668270-12-0]

9

668270-12-0

Research Use Only

...

Linagliptin (GSK2118436) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.

-80°C

51202000