Linopirdine

MedChem Express

Linopirdine [105431-72-9]

9

105431-72-9

Research Use Only

99.08

C26H21N3O

391.474

Linopirdine (DuP 996) is an orally active, selective M-type K + current (IM; Kv7; KCNQ Channels) inhibitor with an IC 50 of 2.4 microM. Linopirdine is a TRPV1 agonist. Linopirdine, a putative cognition enhancing agent, increases acetylcholine release in rat brain tissue [1] [2] [3] .

O=C1N(C2=CC=CC=C2)C3=C(C=CC=C3)C1(CC4=CC=NC=C4)CC5=CC=NC=C5

-20°C,2°C to 8°C

12352200