Linrodostat

MedChem Express

Linrodostat [1923833-60-6]

10

1923833-60-6

Research Use Only

99.81

C24H24ClFN2O

410.91

Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC 50 value of 1.1 nM in IDO1 -HEK293 cells. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers [1] [2] .

O=C(NC1=CC=C(Cl)C=C1)[C@H](C)[C@@](CC2)([H])CC[C@H]2C3=CC=NC4=C3C=C(F)C=C4

-20°C,2°C to 8°C

12352200