LISA-101

Biosynth

LISA-101

7

Research Use Only

gamma-L-Glutamyl-(2S)-gamma-ethyl-gamma-[(3-oxo-3H-phenoxazin-7-yl)oxy]carbonyl-2,4-diaminobutyric acid (Trifluoroacetate Form) (M.W. 514.48) C24H26N4O9 [1638785-74-6] Purity ≥98.0% (HPLC) Fluorogenic Substrate for gamma-Glutamyl Cyclotransferase (GGCT) 1) M. Orlowsli, P. G. Richman and A. Meister, Biochemistry, 1969, 8, 1048-1055; b) A. J. Oakley, T. Yamada, D. Liu, M. Coggan, A. G. Clark and P. G. Board, J. Biol. Chem., 283, 22031 (2008) . (Isolation and Identification of GGCT) 2) P. Gromov, I. Gromova, E. Friis, V. Timmermans-Wielenga, F. Rank, R. Simon, G. Sauter and J. M. A. Moreira, J. Proteome Res., 9, 3941 (2010). (Proteomic Profiling of Mammary Carcinomas) 3) K. Takemura, H. Kawachi, Y. Eishi, K. Kitagaki, M. Negi, M. Kobayashi, K. Uchida, J. Inoue, J. Inazawa, T. Kawano and P.G. Board, Human Pathology, 45, 331 (2014). (GGCT as a Diagnostic Marker in Esophageal Tumors) 4) R. Ran, Y. Liu, H. Gao, Q. Kuang, Q. Zhang, J. Tang, H. Fu, Z. Zhang and Q. He, J.Pharm.Sci., in press (DOI: 10.1002/jps.24163). (siRNA for Treatment of Drug-Resistant Breast Cancer) 5) a) H. Ii, Y. Nishiuchi, T. Yoshiki and T. Yoshiya, Japan patent JP 2014-218494 A; b) T. Yoshiya, H. Ii, S. Tsuda, S. Kageyama, T. Yoshiki and Y. Nishiuchi, manuscript in preparation. (Development of LISA-101)

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