LM11A-31 (dihydrochloride)

MedChem Express

LM11A-31 (dihydrochloride) [1243259-19-9]

10

1243259-19-9

Research Use Only

99.93

C12H27Cl2N3O2

316.27

LM11A-31 dihydrochloride, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimers disease mouse models with mid- to late-stage disease progression [1] [2] .

CC[C@H](C)[C@H](N)C(NCCN1CCOCC1)=O.Cl.Cl

2°C to 8°C

12352200