LMTK3-IN-1

MedChem Express

LMTK3-IN-1

14

Research Use Only

98.74

C18H11F3N4O

356.30

LMTK3-IN-1 (compound C28) is an ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) ( K d =2.5 microM), that acts by degrading LMTK3 via the ubiquitin-proteasome pathway. LMTK3-IN-1 shows anticancer activity in a variety of cancer cell lines and in vivo BC mouse models. LMTK3-IN-1 induces apoptosis in BC cell lines at 10-20 microM [1] .

FC(F)(OC1=CC=CC(C2=CN=C3C=CC(C4=CC=NC=C4)=NN32)=C1)F

-20°C,2°C to 8°C

12352200