Lomeguatrib (PaTrin-2)

Biorbyt

Lomeguatrib (PaTrin-2) [192441-08-0]

16

192441-08-0

Research Use Only

C10H8BRN5OS

326.1724

Lomeguatrib (PaTrin-2) is a modified guanine base, which can repress the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) with an IC50 value of 6 nM.

BrC1=C([H])SC(=C1[H])C([H])([H])OC1C2=C(N=C(N([H])[H])N=1)N=C([H])N2[H]

12352200