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CgoaEWY7M9-EGGINAAAAAJ1NeHw486.png
Lomibuvir
T6729
CAS Number1026785-55-6
Product group Chemicals
Molecular Weight445.61
Overview
- SupplierTargetMol Chemicals
- Product NameLomibuvir
- Delivery Days Customer9
- CAS Number1026785-55-6
- Category SupplierChemical
- Chemical NameLomibuvir
- Molecular FormulaC25H35NO4S
- Molecular Weight445.61
- Scientific DescriptionLomibuvir (VCH-222) (VX-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo -initiated RNA synthesis [1].
- Shelf life instruction3 years
- SMILESN(C(=O)[C@@H]1CC[C@@H](C)CC1)(C2=C(C(O)=O)SC(C#CC(C)(C)C)=C2)[C@@H]3CC[C@@H](O)CC3
- Storage Instruction-20°
- UNSPSC12352200
References
- Yi G, et al. Antimicrob Agents Chemother, 2012, 56(2), 830-837.Read more