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ProductsBack/Longdaysin [1353867-91-0]

Longdaysin [1353867-91-0]

Research Use Only
HY-18285
MedChem Express
CAS Number1353867-91-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.83
Molecular Weight335.33
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Longdaysin [1353867-91-0]
  • Delivery Days Customer
    10
  • CAS Number
    1353867-91-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C16H16F3N5
  • Molecular Weight
    335.33
  • Scientific Description
    Longdaysin is a inhibitor of the Wnt/beta-catenin signaling pathway, which exerts antitumor effect through blocking CK1delta/epsilon-dependent Wnt signaling. Longdaysin inhibits CK1alpha, CK1delta, CDK7, and ERK2 with IC50s of 5.6 microM, 8.8 microM, 29 microM, and 52 microM, respectively[1][2].
  • SMILES
    FC(F)(F)C1=CC=CC(CNC2=NC=NC3=C2N=CN3C(C)C)=C1
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200