Losartan

Biorbyt

Losartan [114798-26-4]

16

114798-26-4

Research Use Only

C22H23ClN6O

422.91

Losartan is a potent, non peptide antagonist of the angiotensin II receptor type 1. This receptor initiates a signal cascade that causes vasoconstriction. Antagonism of this receptor in turn causes vasodilation by blocking the signal from angiotensin II.

ClC1=C(CO)N(CC2=CC=C(C(C=CC=C3)=C3C4=NN=NN4)C=C2)C(CCCC)=N1

12352200