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Losartan Carboxylic Acid (Standard)

HY-12765R
MedChem Express
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More than 130 suppliers
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Losartan Carboxylic Acid (Standard)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Losartan Carboxylic Acid (Standard) is the analytical standard of Losartan Carboxylic Acid. This product is intended for research and analytical applications. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure [1] [2] [3] [4].
  • UNSPSC
    41116135