
WB analysis of human fetal lung tissue using GTX45381 LOXL1 antibody at 0.2-1microg/ml.
LOXL1 antibody, Internal
GTX45381
Overview
- SupplierGeneTex
- Product NameLOXL1 antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID4016
- Target nameLOXL1
- Target descriptionlysyl oxidase like 1
- Target synonymsLOL; LOXL; lysyl oxidase homolog 1; lysyl oxidase-like protein 1
- HostRabbit
- IsotypeIgG
- Protein IDQ08397
- Protein NameLysyl oxidase homolog 1
- Scientific DescriptionThis gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome. [provided by RefSeq, Jan 2016]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203