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Lp-PLA2-IN-10

HY-142778
MedChem Express
Molecular Weight482.36
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lp-PLA2-IN-10
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C21H15F5N4O4
  • Molecular Weight
    482.36
  • Scientific Description
    Lp-PLA2-IN-10 is a potent inhibitor of lipoprotein-associated phospholipase A2 ( Lp-PLA2 ). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-10 has the potential for the research of neurodegenerative-related diseases such as Alzheimers disease (AD), glaucoma, age-related macular degeneration (AMD), or cardiovascular diseases including atherosclerosis (extracted from patent WO2022001881A1, compound 4) [1] .
  • SMILES
    O=C1N=C(C2=C3N(CCN13)CCO2)OCC4=CC(F)=C(C(F)=C4)OC5=CC(C(F)(F)F)=NC=C5
  • UNSPSC
    12352200