LRFN1 antibody

GeneTex

LRFN1 antibody

9

This antibody is predicted to not cross-react with other members of the LRFN family.

WB: 1 - 2 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

LRFN1

leucine rich repeat and fibronectin type III domain containing 1

CTC-246B18.8; leucine-rich repeat and fibronectin type III domain-containing protein 1; SALM2; synaptic adhesion-like molecule 2

Rabbit

IgG

Leucine-rich repeat and fibronectin type III domain-containing protein 1

LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist. This antibody is predicted to not cross-react with other members of the LRFN family.

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203