LRP-6 Protein, Human, Recombinant (mFc)

TargetMol Chemicals

LRP-6 Protein, Human, Recombinant (mFc)

16

Research Use Only

95.3 kDa (predicted). Due to glycosylation, the protein migrates to 110-115 kDa based on Tris-Bis PAGE result.

Low-density lipoprotein receptor protein 6 (LRP6) is a Wnt co-receptor with essential functions in the Wnt/beta-catenin pathway, and mutations in LRP6 gene are linked to many complex human diseases, including metabolic syndrome, cancer, Alzheimers disease and osteoporosis. LRP-6 interacts closely with PDGF receptor beta and TGF-beta receptor 1 at the cell membrane, suggesting that it may have roles in pathways other than WNT/beta-catenin. LRP-6 Protein, Human, Recombinant (mFc) is expressed in HEK293 Cells. The accession number is O75581-1.

-20°C

12352200