Immunohistochemistry of paraffin-embedded Human liver cancer tissue using LRP6 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using LRP6 Polyclonal Antibody at dilution 1:60
LRP6 Polyclonal Antibody
E-AB-17347
Product group Antibodies
Overview
- SupplierElabscience
- Product NameLRP6 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
- UNSPSC12352203