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LRRK2 inhibitor 1

LRRK2 inhibitor 1

T11878
TargetMol Chemicals
CAS Number1802525-61-6
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Product group Chemicals
Molecular Weight397.43
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    LRRK2 inhibitor 1
  • Delivery Days Customer
    9
  • CAS Number
    1802525-61-6
  • Category Supplier
    Chemical
  • Chemical Name
    LRRK2 inhibitor 1
  • Molecular Formula
    C20H23N5O4
  • Molecular Weight
    397.43
  • Scientific Description
    LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.
  • Shelf life instruction
    3 years
  • SMILES
    O(CC)C1=C2C(=NC(NC3=C(OC)C=C(C(=O)N4CCOCC4)C=C3)=N1)NC=C2
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Ding X, et al. Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors. Bioorg Med Chem Lett. 2018 May 15;28(9):1615-1620.
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