LTbetaR-IN-1 [2189366-77-4]

TargetMol Chemicals

LTbetaR-IN-1 [2189366-77-4]

9

2189366-77-4

Chemical

Research Use Only

LTbètaR-IN-1

99.09%

C18H16N4O2

320.35

LTbetaR-IN-1 is a potent and selective lymphin beta receptor (LTbetaR) inhibitor with a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, without affecting the nuclear translocation of p65 mediated by the TNF-alpha receptor. It inhibits p52 nuclear translocation stimulated by TWEAK or Anti-LTbetaR with an IC50 of 10 microM and regulates the NF-kB signaling pathway in a ligand-independent manner.

3 years

C[C@@H](N1Cc2ccccc2C1=O)C(=O)Nc1nc2ccccc2[nH]1

-20°C

51202000