LTBP4 antibody [N1N2], N-term

GeneTex

LTBP4 antibody [N1N2], N-term

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.7 mg/ml

Unconjugated

LTBP4

latent transforming growth factor beta binding protein 4

ARCL1C; latent transforming growth factor-beta binding protein 4L; latent-transforming growth factor beta-binding protein 4; LTBP-4; LTBP4L; LTBP4S

Rabbit

IgG

Latent-transforming growth factor beta-binding protein 4

Transforming growth factor-beta, or TGFB (see TGFB1; MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1; MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF; MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203