Lucidone

MedChem Express

Lucidone

10

Research Use Only

C15H12O4

256.25

Lucidone, an anti-inflammatory agent that can be isolated from the fruit of Lindera erythrocarpa Makino. Lucidone inhibits LPS-induced NO and PGE2 production in RAW 264.7 mouse macrophages. Lucidone also decreases TNF-alpha secretion, iNOS and COX-2 expression. Lucidone prevents NF-kappaB translocation and inhibits JNK and p38MAPK signals. Lucidone also has inhibitory activity against Dengue virus (DENV) (EC50=25 microM)[1][2].

OC(/C=C/C1=CC=CC=C1)=C2C(C(OC)=CC\2=O)=O

12352200