LXR alpha / LXR beta antibody

GeneTex

LXR alpha / LXR beta antibody

9

This antibody detects an ~64 kDa and ~80 kDa protein representing recombinant human LXR alpha and beta.

WB: 1-3 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Rabbit

IgG

Liver X receptors (LXRs), also known as RLD1, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous. The corresponding gene for the LXR is NR1H3.

Human

-20°C or -80°C,2°C to 8°C

12352203