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Western blot analysis of extracts of various cell lines using LXR alpha Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using LXR alpha Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using LXR alpha Polyclonal Antibody at dilution of 1:1000.

LXR alpha Polyclonal Antibody

Research Use Only
E-AB-60633
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    LXR alpha Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • UNSPSC
    12352203