LXRbeta agonist-3

MedChem Express

LXRbeta agonist-3 [2416049-12-0]

10

Research Use Only

C30H33N3O6S

563.66

LXRbeta agonist-3 (compound 4-13) is a potent and selective LXRbeta (liver X receptor beta) agonist, with an EC50 of 0.095 microM. LXRbeta agonist-3 efficiently inhibits U87EGFRvIII cell, with an IC50 of 3.75 microM. LXRbeta agonist-3 shows antitumor activity, and can inhibit glioblastoma[1].

O=C1[C@]2(C3=CC=CC=C3N1)[C@@H](C4=CC(NC5=CC(S(C)(=O)=O)=C(C=C5)CO)=CC=C4)N(CC2)C(OC(C)(C)C)=O

12131703