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LY 3000328 [1373215-15-6]

LY 3000328 [1373215-15-6]

TQ0116
TargetMol Chemicals
CAS Number1373215-15-6
Product group Chemicals
Estimated Purity97.83%
Molecular Weight484.52
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    LY 3000328 [1373215-15-6]
  • Delivery Days Customer
    9
  • CAS Number
    1373215-15-6
  • Certification
    Research Use Only
  • Estimated Purity
    97.83%
  • Molecular Formula
    C25H29FN4O5
  • Molecular Weight
    484.52
  • Scientific Description
    LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S with IC50 values of 7.7 and 1.67 nM for human and mouse cathepsin S, respectively. LY 3000328 (Cathepsin S inhibitor) may slow or prevent abdominal aortic aneurysm (AAA) expansion and/or reduce the risk of AAA rupture by inhibiting cathepsin S-mediated degradation of extracellular matrix proteins, elastin and collagen.
  • SMILES
    CNC(=O)O[C@H]1COc2ccc(cc2[C@@H]1NC(=O)c1ccc(F)cc1)N1CCN(CC1)C1COC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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