LY-411575

Biorbyt

LY-411575 [209984-57-6]

16

209984-57-6

Research Use Only

C26N3O4F2H23

479.4753

LY411575 is a potent gamma-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch clevage with withIC50 of 0.39 nM.

FC1C([H])=C(C([H])=C(C=1[H])[C@@]([H])(C(N([H])[C@@]([H])(C([H])([H])[H])C(N([H])[C@]1([H])C(N(C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C12)=O)=O)=O)O[H])F

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