LY1

MedChem Express

LY1 [2883813-32-7]

10

Research Use Only

98.01

C20H19ClN4O3S

430.91

LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PLpro and Mpro with Kd values of 1.5 microM and 2.3 microM for Mpro C145A protein and PLpro C111A protein, respectively. LY1 potent against the viral proteases, with IC50s of 0.12 microM and 0.99 microM against Mpro and PLpro. LY1 shows high selectivity over other kinases, human proteases and metalloenzyme[1].

O=C1C=C(C2=NS(=O)(C3=C2C1=CC=C3)=O)NC4=C(C=CC=C4)N5CCNCC5.Cl

2°C to 8°C

12131703