LY2811376 [1194044-20-6]
S1528
CAS Number1194044-20-6
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameLY2811376 [1194044-20-6]
- Delivery Days Customer9
- CAS Number1194044-20-6
- CertificationResearch Use Only
- Scientific DescriptionLY2811376 is the first orally available non-peptidic bèta-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM, that act to decrease Abèta secretion with EC50 of 300 nM, demonstrated to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin. Phase 1.
- UNSPSC12352200