LY3056480 [2064292-78-8]

TargetMol Chemicals

LY3056480 [2064292-78-8]

9

Research Use Only

C23H28F3N3O4

467.48

LY3056480 is a gamma-secretase inhibitor (GSI) that inhibits Notch signaling. It demonstrates potential in improving mild to moderate sensorineural hearing loss while maintaining a good safety and tolerance profile. Administered intratympanically, LY3056480 can induce hair cell regeneration and partial hearing restoration in mammals.

N(C([C@@H](NC(CCC(F)(F)F)=O)C)=O)[C@H]1C=2C(N3C(=CC1=O)C(C)(C)CC3)=CC(OC)=CC2

-20°C

12352200