LY314228 [182633-54-1]
HY-117792
CAS Number182633-54-1
Product group Chemicals
Molecular Weight368.43
Overview
- SupplierMedChem Express
- Product NameLY314228 [182633-54-1]
- Delivery Days Customer5
- CAS Number182633-54-1
- CertificationResearch Use Only
- Molecular FormulaC20H24N4O3
- Molecular Weight368.43
- Scientific DescriptionLY314228 is an aminoguanidine 5-HT2 antagonist with relative selectivity for 5-HT2A receptors (IC50: 147.9 nM). The Ki values of LY314228 targeting different 5-HT subtypes are 65 nM (5-HT 2A), 1214 nM (5-HT 2B), and 168 nM (5-HT 2C), respectively. LY314228 is an effective inhibitor of 5-HT-induced paw edema in rats with an ED50 of 6.4 mg/kg in ovariectomized female rats.[1].
- SMILESCCCC1=C(O)C(C(C)=O)=CC=C1COC2=CC=C(/C=N/NC(N)=N)C=C2
- UNSPSC12352200