LYK5 antibody

GeneTex

LYK5 antibody

9

WB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

STRADA

STE20 related adaptor alpha

LYK5, NY-BR-96, PMSE, STRAD, STRAD alpha, Stlk, STE20-related kinase adapter protein alpha, STE20-like pseudokinase, STE20-related kinase adaptor alpha, protein kinase LYK5, serologically defined breast cancer antigen NY-BR-96

Rabbit

IgG

STE20-related kinase adapter protein alpha

The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a pseudokinase. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009]

Human

-20°C or -80°C,2°C to 8°C

12352203