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Chemical Structure
Chemical Structure
Chemical Structure

LysoGlow84 [1782983-52-1]

Research Use Only
AG-CMA-1005
AdipoGen Life Sciences
CAS Number1782983-52-1
Product group Chemicals
Estimated Purity>98%
Molecular Weight246.3 . 113.0
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    LysoGlow84(tm) [1882878-94-5]
  • Delivery Days Customer
    10
  • CAS Number
    1782983-52-1
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C16H12N3 . C2F3O2
  • Molecular Weight
    246.3 . 113.0
  • Scientific Description
    Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric evaluation of pH (F400/440). No esterases are involved, therefore no toxic by-products occur. Long-term stable; is barely metabolized. Fluorescence co-localizes with LysoTracker® Red DND-99. (LysoTracker® is a registered trademark of Molecular Probes, Inc.) - Chemical. CAS: 1782983-52-1. Formula: C16H12N3 . C2F3O2. MW: 246.3 . 113.0. Synthetic. Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric evaluation of pH (F400/440). No esterases are involved, therefore no toxic by-products occur. Long-term stable; is barely metabolized. Fluorescence co-localizes with LysoTracker® Red DND-99. (LysoTracker® is a registered trademark of Molecular Probes, Inc.)
  • SMILES
    [O-]C(=O)C(F)(F)F.[NH2+]1C=NC2=C(N=CC=C12)C1=CC2=CC=CC=C2C=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41116134

References

  • The chemically synthesized Ageladine A-derivative LysoGlow84 stains lysosomes in viable mammalian brain cells and specific structures in the marine flatworm Macrostomum lignano: T. Mordhorst, et al.; Mar. Drugs 13, 920 (2015)