LZCap AG(3Acm) Cas9 mRNA

MedChem Express

LZCap AG(3Acm) Cas9 mRNA

5

Research Use Only

The Cas9 protein, guided by sgRNA, induces DNA double-strand breaks (DSBs) at specific genomic locations, activating the cells endogenous DNA repair mechanisms, non-homologous end joining (NHEJ), or homology-directed repair (HDR), for repairing the targeted DSBs, enabling genome DNA target recognition and cleavage. LZCap AG(3Acm) Cas9 mRNA can be used together with purified sgRNA, where the expressed Cas9 protein acts in conjunction with sgRNA to perform cleavage.

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