Western Blot analysis of Human transitional cell carcinoma tissue, 293T and A172 cell, Human testis tissue and Hela cell using LZTFL1 Polyclonal Antibody at dilution of 1:550
LZTFL1 Polyclonal Antibody
E-AB-11375
Product group Antibodies
Overview
- SupplierElabscience
- Product NameLZTFL1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.4mg/ml
- Scientific DescriptionThis gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.
- UNSPSC12352203